Karen Shatsky was born on May 28, 1987 in Petach Tikva to Shabtai and Ruth who made aliya from Brooklyn, NY in 1984. She was the youngest of six children. Karen lived all her life in Ginot Shomron and studied first at the Masua-Lapidim Elementary School in Karnei Shomron and then the Lehava Ulpana in Kedumim.
On Motzei Shabbat, February 16, 2002, 14-year-old Keren went to do what she most enjoyed - meeting friends at the local Yuvalim shopping mall in Karnai Shomron for some pizza and conversation. Keren was one of three teenagers killed by a suicide bomber who blew himself up outside the pizza store.